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Function Of Key Protein In Cancer Spread Described By LSUHSC Researchers
Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread of cancer. The research will be published in the May 29, 2009 issue of the Journal of Biological Chemistry.

American Lung Association Teams With The AAAAI To Award Research Grants To Study Allergic Respiratory Disease
The American Lung Association and the American Academy of Allergy, Asthma & Immunology are partnering to further clinical research to benefit the estimated 40 to 50 million of Americans living with allergic diseases such as asthma.
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Obama's Proposal To Redirect Abstinence-Only Funding Renews 'Culture-War Battle,' Washington Times Columnist States
President Obama is causing the "core culture-war battle" over sex education to "come full circle" by proposing to redirect funding for abstinence-only sex education to a new Teen Pregnancy Prevention Initiative that "rejects an abstinence-only approach," Washington Times columnist Cheryl Wetzstein writes. According to Wetzstein, Obama"s fiscal year 2010 budget plan "zeroed out" the Title V abstinence-only sex education grant program, set to expire on June 30, and the Community-Based Abstinence Education program. Wetzstein continues that groups supporting comprehensive sex education have "loathed Title V from its inception" because of its "prohibition on teaching teens how to use birth-control products (i.e., no condom demonstrations) and its eight-point definition that seemed utterly unrealistic to sex educators." For example, Title V"s definition said that the ""expected standard of human sexual activity"" was a ""mutually faithful, monogamous relationship in the context of marriage,"" which Wetzstein says she has "heard many times, was insulting to gay youth who couldn"t marry" and "insensitive to minority youth who grew up in neighborhoods where marriage was rare." Wetzstein asks, "What will happen to Title V?" She writes that opponents "are staying vigilant" and working to avoid "any last-minute, back-door revivals of this program." Groups that support abstinence-only sex education are "working the phones, too," Wetzstein reports. According to Wetzstein, Valerie Huber, executive director of the National Abstinence Education Association, noted that "[s]aving Title V will require some heavy lifting, but "it"s expired before and been retroactively renewed."" Wetzstein concludes that "we"ll soon see what happens with the new players in town" (Wetzstein, Washington Times, 6/23).
Endocrinology

AstraZeneca And Mental Health Research Institute In Australia Announce Collaboration To Improve Early Detection Of Alzheimer's Disease

AstraZeneca and The Mental Health Research Institute in Melbourne, Australia, today announced that they have entered into a research collaboration agreement to develop new ways of identifying Alzheimer"s disease patients at early stages of the disease. Researchers aim to find out whether testing cognition at short intervals (every one to three months) over an eighteen-month period will make it possible to identify individuals just at the point at which they are beginning to suffer cognitive decline as a result of Alzheimer"s disease. The study will be conducted in conjunction with The Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL), which aims to improve understanding of the causes and diagnosis of Alzheimer"s disease, and help develop preventative strategies. Alzheimer"s disease is a degenerative brain disease for which there is currently no definitive diagnostic tool. Doctors rely on their clinical judgment to diagnose the disease once it has become symptomatic, but the pathologic process very likely starts a few years beforehand. Professor Paul Maruff, from the Mental Health Research Institute says, "When assessing cognitive function in an individual at risk for dementia on the first occasion, it is often difficult to determine whether their performance on cognitive tests has declined from some previously higher level. The repeated application of a set of brief and simple cognitive measures could therefore help to identify accurately the point when the onset of Alzheimer"s disease was imminent in individual people. This could ultimately lead to a more personalized approach with more effective treatments being given to the right patients at the right time." Dr Judith Jaeger, Director of Neuroscience Early Clinical Development at AstraZeneca adds, "We recognize that in addition to searching for new medicines, we urgently need to find new ways to identify those at risk of developing Alzheimer"s disease before they begin to experience symptoms. In addition to developing a novel approach to diagnosing cognitive decline, we hope that our collaboration with the world-class researchers at The Mental Health Research Institute will provide insights that aid our search for new treatments and ways to prevent disease progression." AstraZeneca


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