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Wisconsin Issues HIV/AIDS Nonprofit Directives For Corrective Action; Clients Protest Service Inadequacies
A group of people living with HIV/AIDS in Madison, Wis., demonstrated in front of the state Department of Health Services to protest what they claim to be inadequate services provided by the AIDS Network and lack of oversight from the state, WISCTV.com reports. State officials conducted a formal review of the nonprofit regarding how the AIDS Network dispersed and tracked services to its clients, and issued the nonprofit 38 directives for corrective action as a result. To date, nearly one-third of the directives have not been fully addressed, according to WISCTV.com. State officials said it will verify compliance on remaining issues in August. AIDS Network Director Karen Dotson said most of the organization"s problems are due to issues related to a new computer system (WISCTV.com, 6/16).

What Is Tinnitus? What Causes Tinnitus?
Tinnitus (from the Latin tinnitus or "ringing") is a condition characterized by ringing, swishing, or other noises that appear to be originating in the ear or head. Not normally a dangerous or serious problem, tinnitus is usually a symptom of some other underlying condition and most often considered a nuisance. Age-related hearing loss, ear injury, foreign objects in the ear, and circulatory system problems, for example, may cause the condition.
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PROTECT-1 Phase II/III Induction-Stage Results For ChemoCentryx's Traficet-EN(TM) Presented In Oral Session At DDW 2009 Conference
ChemoCentryx, Inc., announced that Phase II/III clinical data from the company"s PROTECT-1 (the Prospective Randomized Oral Therapy Evaluation in Crohn"s disease Trial) of Traficet-EN(TM) (CCX282-B) in patients with moderate-to-severe Crohn"s disease demonstrated evidence of clinical efficacy in the reduction of disease severity, as defined by a decrease from baseline in the Crohn"s Disease Activity Index (CDAI) score of at least 70 points over the course of 12 weeks; the more stringent criterion of at least a 100 point decrease in the CDAI score was also met by week 12. In addition, Traficet-EN treatment resulted in colonoscopic evidence of improvement. These data, reported from the Induction Stage of the ongoing PROTECT-1 trial, were presented at Digestive Disease Week (DDW) 2009 in Chicago, IL, by Satish Keshav, M.D., Ph.D., Department of Gastroenterology, John Radcliffe Hospital, Oxford University, in an oral session today.
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Canada Joins International Effort To Provide Access To Health Research

Accelerating the development of discoveries and innovations and facilitating their adoption through free and open access to research findings. This is the aim of an important new initiative that will provide researchers and knowledge users free access to a vast digital archive of published health research at their desktop and connect them to an emerging international network of digital archives anchored in the United States. The Canadian Institutes of Health Research (CIHR), the National Research Council"s Canada Institute for Scientific and Technical Information (NRC-CISTI), and the US National Library of Medicine (NLM) have announced a three-way partnership to establish PubMed Central Canada (PMC Canada). PMC Canada will be a national digital repository of peer-reviewed health and life sciences literature, including research resulting from CIHR funding. This searchable Web-based repository will be permanent, stable and freely accessible. "PMC Canada is a powerful tool that will help researchers build upon one another"s work and speed up the discovery and innovation process to address important health challenges," says Dr. Ian Graham, Vice-President of Knowledge Translation at CIHR. "It will provide quick and easy access to a much broader audience, increasing the value and application of CIHR-funded research." PMC Canada supports CIHR"s recently announced Policy on Access to Research Outputs, under which grant recipients are required to ensure that their peer reviewed publications are freely accessible online within six months of publication. PMC Canada will include a manuscript submission system to enable CIHR-funded researchers to deposit articles that are accepted for publication by peer reviewed journals. PMC Canada builds on the successful PubMed Central (PMC) archive developed by the US National Library of Medicine and will join UK PubMed Central (UKPMC) as a member of the broader PMC International network. This network enables national versions of PMC to share content, and will make much of PubMed Central and UKPMC content accessible through PMC Canada. The network uses software developed by the National Center for Biotechnology Information (NCBI), the division of NLM that created and administers PMC. "We are pleased that Canada is joining the PMC International family, further strengthening this effort to share life sciences literature across the world," says NLM Director Donald A.B. Lindberg, M.D. "International collaboration and data sharing has proven to be a strong driver of scientific advance, with projects such as the GenBank international DNA sequence database propelling new discoveries at a rapid pace. The addition of Canada as a PMCI member should similarly aid the progress of science, while also enhancing public access to the results of research that affects health and health care." CIHR will supply the funds for PMC Canada and NRC-CISTI will contribute its technological expertise to build the infrastructure and manage the repository. "NRC is proud to be a partner in an initiative that will create a permanent archive for Canadian health research and increase access for all Canadians," says Dr. Pierre Coulombe, President, NRC. "This initiative is an important step forward in NRC-CISTI"s efforts to collaborate with others to provide Canadians with seamless and permanent access to scientific, technical and health information." The initial release of PMC Canada, to be available in fall 2009, will include a basic bilingual interface, a manuscript submission system for CIHR researchers and a bilingual help desk. An advisory committee of Canadian health researchers and other stakeholders will guide PMC Canada"s future development. The Canadian Institutes of Health Research


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