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Genetic Test Reduces Need For Second Surgery In Breast Cancer Treatment
A new rapid test can confirm quickly and accurately that breast cancer has most likely not spread into adjacent lymph nodes, offering reassurance to patients and reducing the need for a second operation.

Studies Highlight A Revolutionary New Method Of Treating Post-Operative Bruising
Candela Corporation (Nasdaq: CLZR) announced that two studies have reported superior results on patients who benefited from the Candela Vbeam(R) laser treatments for bruising resulting from cosmetic procedures. The studies concluded that the Vbeam pulsed-dye laser significantly expedited the healing process, improved outcomes, and provided greater overall patient satisfaction.
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Quinine Side Effects May Be Result Of Tryptophan Deficiency
Researchers have found that the anti-malarial drug quinine can block a cell"s ability to take up the essential amino acid tryptophan, a discovery that may explain many of the adverse side-effects associated with quinine. Once confirmed, these findings would suggest that dietary tryptophan supplements could be a simple and inexpensive way to improve the performance of this important drug.
Mental Health

Expression Of Myoglobin In Human Cancers

A group led by Dr. Alberto Bardelli at The University of Turin Medical School reports that myoglobin may protect against the stresses of tumor growth. This study can be found in the July 2009 issue of the American Journal of Pathology. Myoglobin plays an important role in muscle cells by both transporting oxygen and preventing cell damage by scavenging free radicals. Tumor cells often survive in hypoxic (low oxygen), high free radical environments, despite these stresses on tumor growth. Flonta et al hypothesized that certain cancers may express myoglobin to survive the conditions associated with tumor growth. Indeed, human epithelial tumors, including breast, lung, ovary, and colon carcinomas, expressed high levels of myoglobin at early stages of development. In addition, myoglobin was induced in cell lines subjected to hypoxia, oxidative stress, and mitogenic stimulation. Myoglobin expression in carcinomas may therefore protect against the stresses of tumor growth. Dr. Bardelli and colleagues postulate that "should myoglobin prove to play a causative role in tumor progression, ò€¦ it is tempting to speculate that targeting one or more of its multiple functions by pharmacological agents or more advanced molecular tools could represent a novel therapeutic strategy in oncology." Flonta SE, Arena S, Pisacane A, Michieli P, Bardelli A: Expression and Functional Regulation of Myoglobin in Epithelial Cancers. Am J Pathol 2009, 174: 2611-2616 Angela Colmone American Journal of Pathology


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