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Minimal Important Differences In Melanoma-Related Quality Of Life
Quantitative assessments of patient quality of life are becoming increasingly important in the context of clinical trials. In addition to establishing benchmark score differences that are useful when interpreting study results, Minimal Important Differences (MIDs) inform discussions of clinically meaningful change in patient status.

Novavax Announces Selection Of A Respiratory Syncytial Virus Vaccine Candidate For Advanced Preclinical Studies
Novavax, Inc. (Nasdaq: NVAX) announced final selection of a Respiratory Syncytial Virus (RSV) vaccine candidate that will be advanced into additional preclinical studies to support an Investigational New Drug (IND) application. As previously announced, Novavax has been evaluating a number of RSV vaccine candidates, all of which have successfully induced antibody responses in mice. Novavax scientists have now engineered a new vaccine candidate which has been shown to protect mice against RSV disease and can be produced at sufficient yields to allow commercial manufacture. This new candidate is directed against a protein on the surface of the virus, the "F" or "fusion" protein, which is the protein that the virus uses to infect and fuse with cells in the respiratory tract and cause disease.
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Method For Computing Evolutionary Trees Could Revolutionize Evolutionary Biology
Detailed, accurate evolutionary trees that reveal the relatedness of living things can now be determined much faster and for thousands of species with a computing method developed by computer scientists and a biologist at The University of Texas at Austin.
Mental Health

Protect Children From The Allure Of Smoking, Say Doctors

BMA Scotland has warned that children who smoke face years of tobacco addiction that can lead to life-threatening diseases and premature death. The association also called on MSPs to support the proposals contained in the Tobacco and Primary Medical services (Scotland) Bill in order to reduce children"s exposure to tobacco products. Findings in the Scottish Schools Adolescent Lifestyle and Substance Use Survey (SALSUS) published today show that although it is illegal to sell cigarettes to children under the age of 18, 42% of 13 year old regular smokers and 57% of 15 year old regular smokers reported buying cigarettes from a shop and 13% of 13 year old regular smokers and 10% of 15 year old regular smokers from a vending machine. In order to achieve a smokefree Scotland by 2035, BMA Scotland wants to see a robust approach to tobacco control in order to reduce the number of teens who smoke. Dr Peter Terry, Chairman of the BMA in Scotland, said: "It is essential that cigarettes are made less accessible to children. Banning point of sale displays and getting rid of tobacco vending machines will go some way to doing this. "Smoking causes lung cancer, heart disease and respiratory problems. It ages skin, makes your breath smell and stains fingers yellow. Every day doctors witness the death and despair caused by smoking. "We need to break the tobacco trap. Young smokers will become tomorrow"s parents who smoke and they will continue the cycle of smoking-related ill-health." The British Medical Association.


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